Trestolone or MENT (7alpha-methyl-19-nortestostrone) is a compound that has been gaining popularity in the bodybuilding community as a potent steroid for adding quality muscle mass and keeping the sex drive high.
Originally, MENT was investigated as a potential male contraceptive therapy due to its unique chemical properties. Unlike testosterone, MENT cannot bind to 5alpha-reductase, which inhibits the conversion to DHT, making it an ideal candidate for an androgen male contraceptive.
MENT also has minimal affinity for progesterone and mineralocorticoid receptors. Its 7-alpha-methyl group can also inhibit MENT from binding to sex hormone-binding globulin, allowing it to bind only to the androgen receptor and yield the benefits of exogenous androgen use.
Research shows that MENT has anabolic potency 10 times greater than testosterone and is 12 times more suppressive on HTPA. However, it has a very short half-life, calculated to be only 40 min for the unesterified compound.
MENT has been proven to be a safer and more effective form of male contraception compared to testosterone in a comprehensive human study. Many studies have found that MENT is fairly safe on lipids and other biomarkers but definitely needs a PCT to restore LH and FSH levels to normal.